Antifungal activity of clinical Lactobacillus strains against Candida albicans biofilms: identification of potential probiotic candidates to prevent oral candidiasis

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorRossoni, Rodnei Dennis-
Autor(es): dc.creatorde Barros, Patrícia Pimentel-
Autor(es): dc.creatorde Alvarenga, Janaina Araújo-
Autor(es): dc.creatorRibeiro, Felipe de Camargo-
Autor(es): dc.creatorVelloso, Marisol dos Santos-
Autor(es): dc.creatorFuchs, Beth Burgwyn-
Autor(es): dc.creatorMylonakis, Eleftherios-
Autor(es): dc.creatorJorge, Antonio Olavo Cardoso-
Autor(es): dc.creatorJunqueira, Juliana Campos-
Data de aceite: dc.date.accessioned2021-03-11T00:56:32Z-
Data de disponibilização: dc.date.available2021-03-11T00:56:32Z-
Data de envio: dc.date.issued2018-12-11-
Data de envio: dc.date.issued2018-12-11-
Data de envio: dc.date.issued2018-02-07-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1080/08927014.2018.1425402-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/179538-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/179538-
Descrição: dc.descriptionBrown University-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionProcesso FAPESP: 2013/25181-8-
Descrição: dc.descriptionProcesso FAPESP: 2013/26820-4-
Descrição: dc.descriptionProcesso FAPESP: 2015/09770-9-
Descrição: dc.descriptionThis study isolated Lactobacillus strains from caries-free subjects and evaluated the inhibitory effects directly on three strains of C. albicans, two clinical strains and one reference strain. Thirty Lactobacillus strains were isolated and evaluated for antimicrobial activity against in vitro C. albicans biofilms. L. paracasei 28.4, L. rhamnosus 5.2 and L. fermentum 20.4 isolates exhibited the most significant inhibitory activity against C. albicans. Co-incubation between these microorganisms resulted in deterrence of biofilm development and retardation of hyphal formation. The hindrance of biofilm development was characterized by the downregulated expression of C. albicans biofilm-specific genes (ALS3, HWP1, EFG1 and CPH1). L. paracasei 28.4, L. rhamnosus 5.2 and L. fermentum 20.4 demonstrated the ability to exert antifungal activity through the inhibition of C. albicans biofilms.-
Formato: dc.format212-225-
Idioma: dc.languageen-
Relação: dc.relationBiofouling-
Relação: dc.relation0,835-
Relação: dc.relation0,835-
Direitos: dc.rightsopenAccess-
Palavras-chave: dc.subjectBiofilm-
Palavras-chave: dc.subjectCandida albicans-
Palavras-chave: dc.subjectLactobacillus-
Palavras-chave: dc.subjectmycology-
Palavras-chave: dc.subjectpathogenesis-
Título: dc.titleAntifungal activity of clinical Lactobacillus strains against Candida albicans biofilms: identification of potential probiotic candidates to prevent oral candidiasis-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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