A practical guide for comparative genomics of mobile genetic elements in prokaryotic genomes

Registro completo de metadados
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorOliveira Alvarenga, Danillo-
Autor(es): dc.creatorMoreira, Leandro M.-
Autor(es): dc.creatorChandler, Mick-
Autor(es): dc.creatorVarani, Alessandro M.-
Data de aceite: dc.date.accessioned2021-03-11T00:47:20Z-
Data de disponibilização: dc.date.available2021-03-11T00:47:20Z-
Data de envio: dc.date.issued2018-12-11-
Data de envio: dc.date.issued2018-12-11-
Data de envio: dc.date.issued2018-01-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/978-1-4939-7463-4_7-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/175708-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/175708-
Descrição: dc.descriptionMobile genetic elements (MGEs) are an important feature of prokaryote genomes but are seldom well annotated and, consequently, are often underestimated. MGEs include transposons (Tn), insertion sequences (ISs), prophages, genomic islands (GEIs), integrons, and integrative and conjugative elements (ICEs). They are intimately involved in genome evolution and promote phenomena such as genomic expansion and rearrangement, emergence of virulence and pathogenicity, and symbiosis. In spite of the annotation bottleneck, there are so far at least 75 different programs and databases dedicated to prokaryotic MGE analysis and annotation, and this number is rapidly growing. Here, we present a practical guide to explore, compare, and visualize prokaryote MGEs using a combination of available software and databases tailored to small scale genome analyses. This protocol can be coupled with expert MGE annotation and exploited for evolutionary and comparative genomic analyses.-
Formato: dc.format213-242-
Idioma: dc.languageen-
Relação: dc.relationMethods in Molecular Biology-
Relação: dc.relation0,616-
Direitos: dc.rightsopenAccess-
Palavras-chave: dc.subjectClustered regularly interspaced short palindromic repeats-
Palavras-chave: dc.subjectEvolution-
Palavras-chave: dc.subjectGenomic islands-
Palavras-chave: dc.subjectGenomics-
Palavras-chave: dc.subjectInsertion sequences-
Palavras-chave: dc.subjectIntegrative conjugative elements-
Palavras-chave: dc.subjectIntegrons-
Palavras-chave: dc.subjectProphages-
Palavras-chave: dc.subjectTransposons-
Título: dc.titleA practical guide for comparative genomics of mobile genetic elements in prokaryotic genomes-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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