Effects of neonatal clomiphene citrate on fertility and sexual behavior in male rats

Registro completo de metadados
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorPereira, OCM-
Autor(es): dc.creatorConeglian-Marise, MSP-
Autor(es): dc.creatorGerardin, DCC-
Data de aceite: dc.date.accessioned2021-03-10T17:09:49Z-
Data de disponibilização: dc.date.available2021-03-10T17:09:49Z-
Data de envio: dc.date.issued2014-05-20-
Data de envio: dc.date.issued2014-05-20-
Data de envio: dc.date.issued2003-03-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/S1095-6433(02)00355-0-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/17479-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/17479-
Descrição: dc.descriptionIn order to investigate the participation of estrogen during the period of brain sexual differentiation, male rats were treated with clomiphene citrate in the neonatal phase. Fertility and sexual behavior were assessed during adult life. Sexual maturation, body weight, and wet weight of the testes were unchanged. Although the adult male rats treated with clomiphene in the neonatal phase presented a significant reduction in the frequency of mounts, 90% of these rats were able to mate with normal females, which became pregnant. However, these females exhibited a significantly increased number of pre- and post-implantation losses. When these adult male rats were castrated and received estrogen, 60% presented female sexual behavior (receptive behavior and acceptance of mount). Thus, treatment of pups with clomiphene immediately after birth has a long-term effect on the reproductive physiology and sexual behavior of male rats. (C) 2002 Elsevier B.V. All rights reserved.-
Formato: dc.format545-550-
Idioma: dc.languageen-
Publicador: dc.publisherElsevier B.V.-
Relação: dc.relationComparative Biochemistry and Physiology A-molecular & Integrative Physiology-
Relação: dc.relation2.258-
Relação: dc.relation0,836-
Direitos: dc.rightsclosedAccess-
Palavras-chave: dc.subjectantioestrogen-
Palavras-chave: dc.subjectbrain sexual differentiation-
Palavras-chave: dc.subjectclomiphene-
Palavras-chave: dc.subjectestrogen-
Palavras-chave: dc.subjectmale rat-
Palavras-chave: dc.subjectreproduction-
Palavras-chave: dc.subjectsexual behavior-
Título: dc.titleEffects of neonatal clomiphene citrate on fertility and sexual behavior in male rats-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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