Effectiveness of chlorhexidine on the disinfection of complete dentures colonised with fluconazole-resistant Candida albicans: in vitro study

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorde Oliveira Mima, Ewerton Garcia-
Autor(es): dc.creatorPavarina, Ana Claudia-
Autor(es): dc.creatorVargas, Fernanda da Silveira-
Autor(es): dc.creatorGiampaolo, Eunice Teresinha-
Autor(es): dc.creatorMachado, Ana Lucia-
Autor(es): dc.creatorVergani, Carlos Eduardo-
Data de aceite: dc.date.accessioned2021-03-10T17:07:40Z-
Data de disponibilização: dc.date.available2021-03-10T17:07:40Z-
Data de envio: dc.date.issued2014-05-20-
Data de envio: dc.date.issued2014-05-20-
Data de envio: dc.date.issued2011-09-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1111/j.1439-0507.2010.01968.x-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/16446-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/16446-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionCNPq: 503467/2004-9-
Descrição: dc.descriptionThis in vitro study evaluated different concentrations of chlorhexidine (CHX) solution on the disinfection of dentures colonised with a reference (ATCC 90028) and azole-resistant (R1, R2 e R3) strains of Candida albicans. Sterile dentures were individually inoculated with one of the strains and incubated at 37 degrees C for 24 h. Then, each denture was immersed in sterile saline (control) or CHX (2%, 1% or 0.2%) for 10 min. Samples of serial dilutions were spread on Agar Sabouraud Dextrose and incubated at 37 degrees C for 48 h. The colonies were counted and the values of log(cfu ml(-1)) were analysed by Kruskal-Wallis test (P < 0.05). Dentures immersed in CHX were incubated for 7 days. For all strains, the cfu ml(-1) values of 0.2% CHX were significantly higher than those of 2% and 1% CHX. There was no difference between the cfu ml(-1) values of 2% and 1% CHX. For dentures immersed in CHX, ATCC 90028 strain showed lower cfu ml(-1) values than R2 and R3 strains. For control dentures, cfu ml(-1) values of ATCC 90028 strain were higher than those of R strains. Immersion in 2% CHX resulted in the highest number of dentures without fungal growth after 7 days. For denture disinfection, 2% CHX was the most effective concentration, and R strains were less susceptible to disinfection. Chlorhexidine is effective in disinfection of dentures contaminated with azole-resistant C. albicans.-
Formato: dc.formatE506-E512-
Idioma: dc.languageen-
Publicador: dc.publisherWiley-Blackwell-
Relação: dc.relationMycoses-
Relação: dc.relation2.793-
Relação: dc.relation1,069-
Direitos: dc.rightsclosedAccess-
Palavras-chave: dc.subjectCandida albicans-
Palavras-chave: dc.subjectfluconazole-resistance-
Palavras-chave: dc.subjectcomplete dentures-
Palavras-chave: dc.subjectchlorhexidine-
Palavras-chave: dc.subjectazole resistance-
Palavras-chave: dc.subjectdisinfection-
Título: dc.titleEffectiveness of chlorhexidine on the disinfection of complete dentures colonised with fluconazole-resistant Candida albicans: in vitro study-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.