Exposure to crack cocaine causes adverse effects on marine mussels Perna perna

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorMaranho, L. A.-
Autor(es): dc.creatorFontes, M. K.-
Autor(es): dc.creatorKamimura, A. S. S.-
Autor(es): dc.creatorNobre, C. R.-
Autor(es): dc.creatorMoreno, B. B.-
Autor(es): dc.creatorPusceddu, F. H.-
Autor(es): dc.creatorCortez, F. S.-
Autor(es): dc.creatorLebre, D. T.-
Autor(es): dc.creatorMarques, J. R.-
Autor(es): dc.creatorAbessa, D. M. S.-
Autor(es): dc.creatorRibeiro, D. A.-
Autor(es): dc.creatorPereira, C. D. S.-
Data de aceite: dc.date.accessioned2021-03-10T23:56:17Z-
Data de disponibilização: dc.date.available2021-03-10T23:56:17Z-
Data de envio: dc.date.issued2018-11-26-
Data de envio: dc.date.issued2018-11-26-
Data de envio: dc.date.issued2017-10-15-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.marpolbul.2017.08.043-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/163503-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/163503-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionProcesso FAPESP: 2015/17329-0-
Descrição: dc.descriptionCNPq: 402931/2015-7-
Descrição: dc.descriptionOur study aimed to evaluate crack cocaine effects in different life stages of the marine mussel Perna perm. For this purpose, fertilization rate, embryo-larval development, lysosomal membrane stability and DNA strand breaks were assessed. Effect concentrations in gametes and in larval development were found after 1 h (IC50 = 23.53 mg.L-1) and 48 h (IC50 = 16.31 mg.L-1),respectively. The highest tested concentration showing no acute toxicity (NOEC) was 10 mg.L-1, while the lowest observed effect concentration (LOEC) was 20 mg.L-1. NOEC concerning embryo-larval development was 0.625 mg.L-1, while the LOEC was 1.25 mg.L-1. Cyto-genotoxic effects were evidenced in mussels exposed to crack cocaine concentrations ranging from 5 to 500 mu g.L-1. Our results report the first data on effects of an illicit drug to marine organisms and should encourage further ecotoxicological studies of these contaminants of emerging concern in coastal ecosystems.-
Formato: dc.format410-414-
Idioma: dc.languageen-
Publicador: dc.publisherElsevier B.V.-
Relação: dc.relationMarine Pollution Bulletin-
Direitos: dc.rightsopenAccess-
Palavras-chave: dc.subjectCrack cocaine-
Palavras-chave: dc.subjectBioassays-
Palavras-chave: dc.subjectCyto-genotoxicity-
Palavras-chave: dc.subjectMarine organism-
Título: dc.titleExposure to crack cocaine causes adverse effects on marine mussels Perna perna-
Tipo de arquivo: dc.typelivro digital-
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