DOSAGE OF ACETYLCHOLINESTERASE AS A PARAMETER OF PESTICIDE POISONING IN FARMERS IN THE CITY OF MARIALVA/PR (Atena Editora)

Abstract

Over the years, the use of pesticides in agricultural production has increased in Brazil, with the aim of ensuring excellent production of grains and cereals. The Southeast, South and Central-West regions are respectively those that make the most use of these agrochemicals. There are numerous classes of these substances, the most used of which are organophosphates (OF), a class responsible for combating the vast majority of agricultural pests and causing poisoning if they are handled incorrectly and without the use of personal protective equipment. Pesticides in general inhibit the function of the enzyme acetylcholinesterase, which has the physiological function of degrading the neurotransmitter acetylcholine. When the enzyme is inhibited, acetylcholine accumulates in the synaptic cleft, causing some signs and symptoms, as is the case with pesticide poisoning. Since farmers are responsible for producing food that supplies countries, they need to guarantee excellent products, where pesticides are applied in order to produce quality food. Thus, a survey was carried out with farmers, together with a questionnaire that was applied to them, where it was possible to achieve the objectives of this study, analyzing 81 farmers in their daily activities and measuring Cholinesterase in each of them, evaluating possible poisoning. by pesticides. Based on the literature, it was possible to relate this study to existing studies.