Antihypertensive Medications and Brain Function: Mechanisms Underlying Beneficial and Harmful Therapeutic Neuropsychiatric Effects (Atena Editora)

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Autor(es): dc.contributor.authorCRUZ, MILENA DA COSTA-
Autor(es): dc.contributor.authorSILVA, MAGNO FARACO DA-
Autor(es): dc.contributor.authorREZENDE, ISABELA DOS SANTOS DE-
Autor(es): dc.contributor.authorGROSSI, LETÍCIA DE OLIVEIRA-
Autor(es): dc.contributor.authorAISSA, JULIANA MACIEL-
Autor(es): dc.contributor.authorCORRÊA, VICTORIA GOELZER FERREIRA LASCH-
Autor(es): dc.contributor.authorALTOÉ, RAFAELA VALDIERO-
Autor(es): dc.contributor.authorGATTI, AMANDA BOTTE-
Autor(es): dc.contributor.authorCOELHO, MAURICIO GOMES PESSOA-
Autor(es): dc.contributor.authorBEDESCHI, MARIA CLARA PEREIRA CORREIA-
Autor(es): dc.contributor.authorPERUGINI, MARIANA LIPPAUS SÓRIA-
Autor(es): dc.contributor.authorSACRAMENTO, NEIDEJANY DE ASSUNÇÃO DO-
Data de aceite: dc.date.accessioned2024-01-30T20:50:23Z-
Data de disponibilização: dc.date.available2024-01-30T20:50:23Z-
Data de envio: dc.date.issued2024-01-30-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/741793-
Resumo: dc.description.abstractGoal: To evaluate and synthesize the scientific evidence available in current literature on the effects of antihypertensive medications on brain function, focusing on the mechanisms underlying beneficial and harmful therapy. Methods: Narrative bibliographic review carried out through the PubMed database by applying the search strategy “hypertension”, “antihypertensive”, “Brain function”, “neurological”, “symptons”, in association with the Boolean operators “OR” and “AND”, resulting in 1,471 initial articles. After applying the inclusion and exclusion criteria, only 19 studies became official sources of the work. Discussion: The blood pressure control caused by the use of antihypertensive drugs leads to an improvement in microvascular function with a consequent impact on reducing inflammation in brain cells, which appears to be promising for preventing possible cognitive decline in patients with mild impairment. Final considerations: In elderly patients with dementia, the concrete effect of using antihypertensives is controversial. In this aspect, it is noteworthy that there are still gaps in the literature regarding the effectiveness, effects and management of antihypertensive drugs in alleviating neuropsychiatric disorders.pt_BR
Idioma: dc.language.isoenpt_BR
Palavras-chave: dc.subjectAntihypertensivept_BR
Título: dc.titleAntihypertensive Medications and Brain Function: Mechanisms Underlying Beneficial and Harmful Therapeutic Neuropsychiatric Effects (Atena Editora)pt_BR
Tipo de arquivo: dc.typelivro digitalpt_BR
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