ANALYSIS OF HYPERTHYROIDISM REMISSION AFTER SUSPENSION OF THIONAMIDE WITH PROLONGED USE: A CROSS-CROSS-SET STUDY (Atena Editora)

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MetadadosDescriçãoIdioma
Autor(es): dc.contributor.authorALBUQUERQUE, MANUELA WANDERLEY CARNEIRO DE-
Autor(es): dc.contributor.authorOLIVEIRA, SARA LINDA BARBOSA GONDIM DE-
Autor(es): dc.contributor.authorARRUDA, PATRÍCIA FERNANDES BORBA DE-
Autor(es): dc.contributor.authorALMEIDA, MARCOS OLIVEIRA PIRES DE-
Data de aceite: dc.date.accessioned2023-12-07T03:39:26Z-
Data de disponibilização: dc.date.available2023-12-07T03:39:26Z-
Data de envio: dc.date.issued2023-12-06-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/740250-
Resumo: dc.description.abstractGoals: evaluate the laboratory evolution of hyperthyroid patients, who used thionamides for at least 3 years, after discontinuing the drug. Methods: Cross-sectional study with an analytical component, developed between 2017-2018 in Limoeiro-PE- Brazil, using data from medical records in UPAE patients, on hormonal dosage values for one year after stopping the medication. Results: Among the 56 patients, women were 82.1%, age <40 years in 51.8%, methimazole as the drug used in 91.1%. Most patients had initial TRAb ≥ 3.5 IU/L (80.4%), TRAb in suspension <3.0 IU/L (80.4%) and TSH in suspension 3.0 IU/L in 58.9%. After discontinuation of the drug, 53.6% of patients remitted. Remission was present in 100% of those with initial TRAb <3.5IU/L and in 42.2% of those with initial TRAb ≥ 3.5IU/L. None of the patients with TRAb on drug suspension ≥ 3.0IU/L remitted. Of those who had TSH < 3.0 IU/L upon suspension, 13% remitted, while those with TSH 3.0 IU/L 81.8% achieved remission. Conclusion: remission of hyperthyroidism occurs in about half of patients who use antithyroid drugs for at least three years. The value of initial TRAb and TRAb and TSH after stopping the drug are also predictors of disease remission.pt_BR
Idioma: dc.language.isoenpt_BR
Palavras-chave: dc.subjectHyperthyroidismpt_BR
Título: dc.titleANALYSIS OF HYPERTHYROIDISM REMISSION AFTER SUSPENSION OF THIONAMIDE WITH PROLONGED USE: A CROSS-CROSS-SET STUDY (Atena Editora)pt_BR
Tipo de arquivo: dc.typelivro digitalpt_BR
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