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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor.author | SILVA, JOVANNA EDUARDA COELHO | - |
Autor(es): dc.contributor.author | CASTILHAS, JÉSSICA HIPÓLITO | - |
Autor(es): dc.contributor.author | SOUSA, SAMANTHA COSTA DE | - |
Autor(es): dc.contributor.author | GUIMARÃES, ANA CAROLINA DE SOUSA | - |
Autor(es): dc.contributor.author | GAMA, JAMILE POMPERMAIER | - |
Autor(es): dc.contributor.author | SOUSA, LARA CRISTINA VIEIRA | - |
Autor(es): dc.contributor.author | MOREIRA, LEONARDO CARUBA | - |
Autor(es): dc.contributor.author | RIBEIRO, MARINA MOREIRA | - |
Autor(es): dc.contributor.author | MENELLI, HENRIQUE PESSOTI | - |
Autor(es): dc.contributor.author | PENHA, TAINARA PAULA DA ANUNCIAÇÃO | - |
Autor(es): dc.contributor.author | REIS, MARIA ANGÉLICA OTERO DE MELO DOS | - |
Autor(es): dc.contributor.author | SILVEIRA, MYRNA | - |
Data de aceite: dc.date.accessioned | 2023-07-13T11:30:40Z | - |
Data de disponibilização: dc.date.available | 2023-07-13T11:30:40Z | - |
Data de envio: dc.date.issued | 2023-06-30 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/capes/733997 | - |
Resumo: dc.description.abstract | Purpose: examine the literature on the role of vitamin D in the evolution and exacerbation of mood disorders, with a focus on bipolar and depressive disorders. Methodology: Literature review in the PubMed database. Through the following search strategy: vitamin D AND (bipolar disorder OR mood disorders). After applying the inclusion and exclusion criteria, 15 articles were selected to compose the collection of this study. Results: Vitamin D plays two main roles in the body. The first is related to the regulation of the immune system, where it suppresses the production of pro-inflammatory cytokines and increases levels of anti-inflammatory ones. This role is relevant in the context of bipolar disorder, which is associated with increased pro-inflammatory cytokines. The second paper focuses on the mechanisms linked to depression, specifically in the hypothalamic-pituitary-adrenal axis. In this context, vitamin D acts as an antagonist of glucocorticoids, which are excessively active in these disorders. Furthermore, there is evidence that vitamin D can also regulate the formation of new neurons in the hippocampus. Final considerations: Vitamin D plays a significant role in the evolution and exacerbation of disorders, being essential for the proper functioning of the central nervous system and for the regulation of the immune system. | pt_BR |
Idioma: dc.language.iso | en | pt_BR |
Palavras-chave: dc.subject | Depression | pt_BR |
Título: dc.title | THE ROLE OF VITAMIN D IN THE DEVELOPMENT/WORSEAGE OF MOOD DISORDERS, WITH A FOCUS ON BIPOLAR AFFECTIVE DISORDER AND DEPRESSION (Atena Editora) | pt_BR |
Tipo de arquivo: dc.type | livro digital | pt_BR |
Aparece nas coleções: | Livros digitais |
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