SIBUTRAMINE: THE MAGIC PILL TO LOSE WEIGHT AND INCREASE CARDIOVASCULAR RISKS (Atena Editora)

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MetadadosDescriçãoIdioma
Autor(es): dc.contributor.authorAMORIM, VINICYUS EDUARDO MELO-
Autor(es): dc.contributor.authorSANTOS, ANA CAROLINA BEZERRA CHAGAS-
Autor(es): dc.contributor.authorFILHO, DANIEL SOARES-
Autor(es): dc.contributor.authorSILVA, FELIPE SANTOS DA-
Autor(es): dc.contributor.authorAURELIANO, PRISCILA CARDOSO ALVES-
Autor(es): dc.contributor.authorSARAIVA, MARIA BEATRIZ BRITO-
Autor(es): dc.contributor.authorMARTINO, VICTOR DE-
Autor(es): dc.contributor.authorSANTOS, IRLANÍ LIMA DOS-
Autor(es): dc.contributor.authorBRITO, THIAGO MARQUES-
Autor(es): dc.contributor.authorSILVA, GUSTAVO JOSIVALDO DA-
Autor(es): dc.contributor.authorNETO, PAULO ROBERTO DE ANDRADE-
Autor(es): dc.contributor.authorPEREIRA, TADEU MELO DE ARAUJO-
Data de aceite: dc.date.accessioned2023-04-18T12:38:12Z-
Data de disponibilização: dc.date.available2023-04-18T12:38:12Z-
Data de envio: dc.date.issued2023-04-05-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/725700-
Resumo: dc.description.abstractObesity is a complex and multifactorial condition that affects an increasing number of people around the world. While lifestyle changes such as the diet and exercise are the cornerstone of obesity treatment, in some cases pharmacological treatment may be necessary. Sibutramine is a drug that has been widely used for the treatment of obesity, acting as a serotonin and noradrenaline reuptake inhibitor, resulting in appetite suppression and increased satiety. However, several clinical trials and observational studies have found significant associations between sibutramine use and adverse cardiovascular effects, including increased blood pressure, heart rate, and risk of cardiovascular events such as myocardial infarction and stroke. Faced with the side effects of sibutramine, many countries suspended the marketing of this drug, restricting its use only to extreme cases of obesity. Nowadays, the most used drugs for the treatment of obesity include orlistat, liraglutide and phentermine/topiramate, which have a lower risk of adverse cardiovascular effects. In summary, pharmacological treatment of obesity may be an option for patients with severe obesity who have not had success with lifestyle changes. However, it is essential to carefully assess the risks and benefits of each medication before prescribing it, taking into account the patient's comorbidities and clinical conditions. Sibutramine, despite its effectiveness in weight control, should be used with caution due to its adverse cardiovascular effects.pt_BR
Idioma: dc.language.isoenpt_BR
Palavras-chave: dc.subjectsibutraminept_BR
Título: dc.titleSIBUTRAMINE: THE MAGIC PILL TO LOSE WEIGHT AND INCREASE CARDIOVASCULAR RISKS (Atena Editora)pt_BR
Tipo de arquivo: dc.typelivro digitalpt_BR
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