Atenção: Todas as denúncias são sigilosas e sua identidade será preservada.
Os campos nome e e-mail são de preenchimento opcional
Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor.author | PIANA, GABRIEL SALINA | - |
Autor(es): dc.contributor.author | BATISTA, CAROLINA DE CARVALHO LIMA | - |
Autor(es): dc.contributor.author | CONTÃO, HELENA DE OLIVEIRA | - |
Autor(es): dc.contributor.author | LOPES, KEILANE AZEVEDO | - |
Autor(es): dc.contributor.author | SILVA, LETÍCIA TAVARES DELÁDIO | - |
Autor(es): dc.contributor.author | CARDOSO, THAÍS CIOTTO | - |
Autor(es): dc.contributor.author | ASSUNÇÃO, GIOVANA NUNES DE | - |
Autor(es): dc.contributor.author | ZAMPROGNO, SOPHIA BRIDI | - |
Autor(es): dc.contributor.author | CAVALCANTE, RAFAEL LEITUGA DE CARVALHO | - |
Autor(es): dc.contributor.author | BORGES, SILANA RAQUEL ALMEIDA | - |
Autor(es): dc.contributor.author | REIS, MARIA ANGÉLICA OTERO DE MELO DOS | - |
Autor(es): dc.contributor.author | MATA, JAQUELINE PEREIRA DA | - |
Data de aceite: dc.date.accessioned | 2023-01-25T12:13:34Z | - |
Data de disponibilização: dc.date.available | 2023-01-25T12:13:34Z | - |
Data de envio: dc.date.issued | 2022-12-23 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/capes/720448 | - |
Resumo: dc.description.abstract | Goal: To discuss, through the scientific literature, the association between the balance of the intestinal microbiota and the emergence of neurodegenerative disorders, especially Alzheimer's disease (AD). Methods: Literature review carried out from October to November 2022 through searches in the following PubMed database. 248 articles were selected and, after inclusion criteria, 17 studies were selected to compose this review. Review: The different studies analyzed indicate that the microbiota-intestine-brain axis is closely interconnected and involved in neural and brain functioning. Its participation consists of processes of cognitive regulation and aging processes, which are directly related to intestinal dysbiosis and its repercussions at the level of the central nervous system (CNS). Intestinal dysbiosis may be in the process of biological senescence and culminate in chronic systemic inflammation, with the potential for brain beta-amyloid aggregation. Final Considerations: There is an imbalance of the intestinal microbiota that is related to neurodegenerative diseases. As the pathophysiology of AD is multifactorial, it is still necessary to deepen studies on this relationship to aid in early diagnosis and treatment. | pt_BR |
Idioma: dc.language.iso | en | pt_BR |
Palavras-chave: dc.subject | Microbiota-gut-brain axis | pt_BR |
Palavras-chave: dc.subject | Alzheimer's disease | pt_BR |
Título: dc.title | THE POTENTIAL ROLE OF THE INTESTINAL MICROBIOTA IN THE MANIFESTATION OF ALZHEIMER'S DISEASE: A LITERATURE REVIEW (Atena Editora) | pt_BR |
Tipo de arquivo: dc.type | livro digital | pt_BR |
Aparece nas coleções: | Livros digitais |
O Portal eduCAPES é oferecido ao usuário, condicionado à aceitação dos termos, condições e avisos contidos aqui e sem modificações. A CAPES poderá modificar o conteúdo ou formato deste site ou acabar com a sua operação ou suas ferramentas a seu critério único e sem aviso prévio. Ao acessar este portal, você, usuário pessoa física ou jurídica, se declara compreender e aceitar as condições aqui estabelecidas, da seguinte forma: