MUCOSITIS INDUCED BY CHEMOTHERAPY: PATHOPHYSIOLOGY AND STRATEGIES TO IMPROVE INTESTINAL RESISTANCE (Atena Editora)

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Autor(es): dc.contributor.authorDELMONDES, JORDANIA SAUANY LUCENA-
Autor(es): dc.contributor.authorSILVA, THALITA DE JESUS DA-
Autor(es): dc.contributor.authorSOLETTI, CAROLINA-
Autor(es): dc.contributor.authorKRIGER, LARA ASSUNÇÃO-
Autor(es): dc.contributor.authorAGUIAR, ALESSANDRA NUNEZ DE-
Autor(es): dc.contributor.authorMROZINSKI, GABRIELA NAIRANA PEDROSO-
Autor(es): dc.contributor.authorRODRIGUES, PEDRO HENRIQUE TAUFER-
Autor(es): dc.contributor.authorGASPAR, BEATRIZ FERREIRA-
Autor(es): dc.contributor.authorMARCUCCI, MICHELLE LOPES-
Autor(es): dc.contributor.authorSANTOS, THAÍS LAMOUNIER-
Autor(es): dc.contributor.authorCECCON, TAÍSE CÁSSIA DIAS-
Autor(es): dc.contributor.authorSACRAMENTO, NEIDEJANY DE ASSUNÇÃO DO-
Data de aceite: dc.date.accessioned2023-01-23T14:26:01Z-
Data de disponibilização: dc.date.available2023-01-23T14:26:01Z-
Data de envio: dc.date.issued2022-12-06-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/720356-
Resumo: dc.description.abstractGoal: To identify the relationship between the onset of intestinal mucositis in cancer patients undergoing chemotherapy and the influence of the degree of immunosuppression.Methodology: Literature review conducted through searches in the PubMed database, in which 286 articles were found and selected, after the of inclusion, 11 studies to compose. Discussion: Intestinal mucositis induced by chemotherapy is a major difficulty faced by patients who use chemotherapy, manifesting itself in 40% of patients with a standard dose of the drug and in 100% of patients undergoing high doses. It is noted that the occurrence of intestinal mucositis is also influenced by the age of the patients, the presence of underlying comorbidities and the type of chemotherapy used. Final Considerations: The most related drugs are methotrexate, cisplatin, irinotecan (CPT-11), oxaliplatin, irinotecan and 5-FU. In addition, there is a higher prevalence in patients of advanced age who have diabetes or autoimmune diseases. Such factors can compromise adherence to treatment and lead to a drastic reduction in the quality of life of patients.pt_BR
Idioma: dc.language.isoenpt_BR
Palavras-chave: dc.subjectIntestinal Mucositispt_BR
Palavras-chave: dc.subjectAntineoplasticspt_BR
Título: dc.titleMUCOSITIS INDUCED BY CHEMOTHERAPY: PATHOPHYSIOLOGY AND STRATEGIES TO IMPROVE INTESTINAL RESISTANCE (Atena Editora)pt_BR
Tipo de arquivo: dc.typelivro digitalpt_BR
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