MESENTERIC THROMBOSIS AND VACCINATION AGAINST COVID-19: IS THERE A RELATIONSHIP?

Abstract

The COVID-19 pandemic has caused thousands of people around the world to die in recent years, however, with the advent of vaccination, mortality from the SARS-CoV-2 virus has been drastically reduced. Therefore, since the beginning of vaccination, mainly vaccines using recombinant vector technology, there have been reports of related thromboembolic events. Presenting a case report of a male patient, 63 years old, who developed an acute abdomen 14 days after vaccination with the recombinant type. He had a single history of deep venous thrombosis. Abdominal tomography with report of multiple loops of the middle and distal ileum in the mesogastrium and right iliac fossa showing an edematous appearance, with reduced parietal contrast, associated with diffuse densification of the adjacent mesentery, with a small to moderate amount of free fluid around it. Filling defect compatible with a thrombus extending from the lumen of the right ileocolic venous branches of the superior mesenteric vein, extending to the extra and intrahepatic portal vein. Exploratory laparotomy was performed with identification of ischemia in the small intestine measuring approximately 60cm, with enterectomy and primary anastomosis. He was discharged on the fifth day of postoperative evolution with follow-up with general surgery and hematology. We know that SARS-CoV-2 infection has a high thrombogenic potential, and comparing the risk and benefit of administering vaccination with the decrease in mortality, it is important to maintain vaccine programs, but it is of paramount importance that health services understand and investigate Vaccine-induced thrombotic thrombocytopenia and its possible complications, including surgical ones.