VON WILLEBRAND DISEASE IN DOGS: A GENETIC APPROACH (Atena Editora)

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MetadadosDescriçãoIdioma
Autor(es): dc.contributor.authorCOSTA, HÉLEN CLARICE CHAVES-
Autor(es): dc.contributor.authorFERNANDES, ALÍCIA OLIVEIRA-
Autor(es): dc.contributor.authorMELO, JULIANA MELKA DE CARVALHO ABREU-
Autor(es): dc.contributor.authorSILVA, LYANCA KARLA LIMA-
Autor(es): dc.contributor.authorFILHO, REMY LIMA DE CARVALHO-
Autor(es): dc.contributor.authorSANTOS, ANA PAULA LOPES-
Autor(es): dc.contributor.authorSOUZA, HELLEN CRISTINA SILVA DE-
Autor(es): dc.contributor.authorARAÚJO, MIKAELLY GOMES DE-
Autor(es): dc.contributor.authorPENHA, NARA GRAZIELLE GOMES-
Autor(es): dc.contributor.authorPIRES, SABRINA STEFANY DE OLIVEIRA-
Autor(es): dc.contributor.authorDIAS, HELDER LUÍS CHAVES-
Data de aceite: dc.date.accessioned2022-08-25T13:11:54Z-
Data de disponibilização: dc.date.available2022-08-25T13:11:54Z-
Data de envio: dc.date.issued2022-08-10-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/714790-
Resumo: dc.description.abstractVon Willebrand disease (VWD) is a common hereditary or acquired bleeding disorder in dogs, and is characterized by an abnormality in Von Willebrand factor (VWF), which is a glycoprotein that plays an essential role in platelet adhesion and aggregation during primary hemostasis. Most dog breeds, including the Dobermann, have DvW type I, with autosomal dominant inheritance with incomplete penetrance in some breeds and autosomal recessive in others, caused by a decrease in the total concentration of vWf, with all multimers present, but in reduced amounts. Given the importance of this disease, taking into account the clinical signs, such as prolonged bleeding, the objective literature review, through a survey of the literature, develop and detail scientific, genetic and clinical knowledge in relation to Von Willebrand disease in dogs, in addition to understanding the genetic influence on the severity and transmission of the disease.pt_BR
Idioma: dc.language.isoenpt_BR
Palavras-chave: dc.subjectWILLEBRANDpt_BR
Título: dc.titleVON WILLEBRAND DISEASE IN DOGS: A GENETIC APPROACH (Atena Editora)pt_BR
Tipo de arquivo: dc.typelivro digitalpt_BR
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