PSEUDOMEMBRANOUS COLITIS RESULTING FROM THE USE OF ANTIBACTERIALS A SYSTEMATIC REVIEW (Atena Editora)

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MetadadosDescriçãoIdioma
Autor(es): dc.contributor.authorFILHO, ROGÉRIO GOMES DE MELO-
Autor(es): dc.contributor.authorBARBOSA, LAURA CHAVES-
Autor(es): dc.contributor.authorFERREIRA, ÁLVARO FERNANDES-
Autor(es): dc.contributor.authorBRAVO, KÁRITA FERNANDA DE OLIVEIRA RODRIGUES-
Autor(es): dc.contributor.authorNASCIMENTO, NATHÁLIA CRISTINE ALVES DO-
Autor(es): dc.contributor.authorPARREIRA, ANDRESSA MORGADO-
Autor(es): dc.contributor.authorVAZ, SARAH REZENDE-
Autor(es): dc.contributor.authorCARRIJO, BEATRIZ VIEIRA-
Autor(es): dc.contributor.authorBARBOSA, BÁRBARA IZARIAS-
Autor(es): dc.contributor.authorMACHADO, ANA CLARA LIMA-
Autor(es): dc.contributor.authorOLIVEIRA, GUSTAVO BATISTA-
Autor(es): dc.contributor.authorARAÚJO, VANESSA SOARES DE-
Data de aceite: dc.date.accessioned2022-07-29T14:56:19Z-
Data de disponibilização: dc.date.available2022-07-29T14:56:19Z-
Data de envio: dc.date.issued2022-07-20-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/705530-
Resumo: dc.description.abstractPseudomembranous colitis is an inflammatory condition of the colon characterized by raised whitish-yellow plaques that coalesce to form pseudomembranes on mucosal surfaces. Antibacterial treatment is the main risk factor for the development of pseudomembranous colitis through the interruption of resistance to colonization of the intestinal microbiota, which favors colonization by the Clostridium difficile. This article is a systematic review of the literature, using the PubMed database. Were selected 14 articles using the descriptors: “pseudomembranous enterocolitis AND antibacterials”. Studies have shown that under normal conditions, this human gut microbiota can prevent the colonization of pathogens through general mechanisms, such as direct inhibition by bacteriocins, nutrient depletion, or stimulation of the host's immune defenses. However, treatment with broad-spectrum antibacterials preceding C infection. difficile disturbs the normal balance of the colonic microbiota, creating a more hospitable environment for the growth of C. difficile. Therefore, the use of antibacterials is the main responsible for the disruption of the intestinal microbiota and, consequently, for the reduction of resistance to colonization, which favors the infection by C. difficile and the development of pseudomembranous colitis.pt_BR
Idioma: dc.language.isoenpt_BR
Palavras-chave: dc.subjectANTIBACTERIALpt_BR
Título: dc.titlePSEUDOMEMBRANOUS COLITIS RESULTING FROM THE USE OF ANTIBACTERIALS A SYSTEMATIC REVIEW (Atena Editora)pt_BR
Tipo de arquivo: dc.typelivro digitalpt_BR
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