COPAIBA OIL-RESIN IMPROVES PONDERAL DEVELOPMENT AND ATTENUATES INFLAMMATION IN ADIPOSE TISSUE IN A MODEL OF HEPATIC CIRRHOSIS (Atena Editora)

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Autor(es): dc.contributor.authorROCHA, LARA ALVES-
Autor(es): dc.contributor.authorPAULA, MATEUS GONÇALVES DE-
Autor(es): dc.contributor.authorTELLES, LUCIANA ORTEGA-
Autor(es): dc.contributor.authorSILVA, THAIS PEREIRA DA-
Autor(es): dc.contributor.authorPAULINO, ANGÉLICA MACEDO BORGES-
Autor(es): dc.contributor.authorMENDONÇA, SABRINA TRIGUEIRO-
Autor(es): dc.contributor.authorNASCIMENTO, ANDRÉ FERREIRA DO-
Autor(es): dc.contributor.authorBOMFIM, GISELE FACHOLI-
Autor(es): dc.contributor.authorLUVIZOTTO, RENATA DE AZEVEDO MELO-
Data de aceite: dc.date.accessioned2022-05-24T19:32:37Z-
Data de disponibilização: dc.date.available2022-05-24T19:32:37Z-
Data de envio: dc.date.issued2022-05-19-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/703077-
Resumo: dc.description.abstractThe aim of this study was to evaluate the effect of copaiba oil-resin on body weight, adiposity and inflammatory markers in adipose tissue in animals with liver cirrhosis. Male Wistar rats were randomly divided into two groups: Liver Cirrhosis (CH, n=7) and CH + copaiba oil-resin (CH+OC, n=7). Liver cirrhosis was induced by intraperitoneal (i.p.) administration of thioacetamide at a dose of 100mg/kg/twice a week; and copaiba oil-resin supplementation was administered, via gavage, at a dose of 200mg/kg/day for 8 weeks. The data show that copaiba oil-resin supplementation was able to improve weight gain and adiposity in animals with liver cirrhosis, in addition to increasing the levels of IL-10, an anti-inflammatory cytokine, and reducing the levels of IL-10. 1β, pro-inflammatory cytokine. These findings suggest a beneficial effect of copaiba oil-resin on adipose tissue in a liver cirrhosis model.pt_BR
Idioma: dc.language.isoenpt_BR
Palavras-chave: dc.subjectINFLAMMATIONpt_BR
Título: dc.titleCOPAIBA OIL-RESIN IMPROVES PONDERAL DEVELOPMENT AND ATTENUATES INFLAMMATION IN ADIPOSE TISSUE IN A MODEL OF HEPATIC CIRRHOSIS (Atena Editora)pt_BR
Tipo de arquivo: dc.typelivro digitalpt_BR
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