EFFECTS OF THE USE OF CURCUMIN IN PATIENTS WITH ORAL LESIONS: A LITERATURE REVIEW (Atena Editora)

Abstract

Curcumin is a phytotherapic extracted from turmeric that has Turmeric in its composition. In the meantime, it is observed in the sociocultural context that its use has been widely used to treat some oral lesions in dentistry, highlighting its effects on Carious Lesions (LC), Recurrent Aphthous Stomatitis (RAS), Oral Lichen Planus (LPO) and oral mucositis (OM). In order to verify the effects of using curcumin in patients with oral lesions, a search was carried out on the SciELO platform and on the scientific databases Science Direct, Scopus, PubMed, VHL (Medline, LILACS), using the descriptors “curcumin”, “oral lesions” and “dentistry” with the help of the Boolean operator “and”, in addition to delimiting the search for systematic review studies, in the time interval 2017 to 2022. 361 scientific articles were found, but only 5 articles were selected because they meet the objective of the present study. Curcumin has anti-inflammatory, antioxidant, anticancer and immunomodulatory effects. From this perspective, oral lesions treated with curcumin promote in CL cases the reduction of bacterial activity and biofilm reduction, also in RAS cases, relief of the signs and symptoms of the disease, as well as in OLP cases, reducing pain, burning sensation and clinical appearance of lesions and cases of OM, which reduce pain, erythema intensity, ulceration area and even the degree of severity of this condition. Thus, it is observed that the use of curcumin in the face of the aforementioned oral lesions has several beneficial effects, given its high anti-inflammatory, antioxidant, antibacterial, immunomodulatory and, above all, anticancer potential, which reduces the signs and symptoms of CL, RAS conditions, LPO and MO.